Select Publications

2019/

Blood-brain barrier dysfunction in aging induces hyper-activation of TGF-beta signaling and chronic yet reversible neural dysfunction.

Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., … Kaufer, D. Science Translational Medicine. [In Press]

Paroxysmal slow cortical activity in Alzheimer’s disease and epilepsy is associated with blood-brain barrier dysfunction

Milikovsky, D. Z., Ofer, J., Senatorov, V. V., Friedman, A. R., Sheintuch, L., Elazari, N., ... Kaufer, D., Friedman, A. Science Translational Medicine. [In Press]

2018/

Concussion, Microvascular Injury, and Phosphorylated Tauopathy in Young Athletes after Impact Head Injury and an Impact Concussion Mouse Model.

Tagge CA, Fisher AM, Minaeva OV et al.....Goldstein L. BRAIN. https://doi.org/10.1093/brain/awx350

2019/

Blood-brain barrier dysfunction in aging induces hyper-activation of TGF-beta signaling and chronic yet reversible neural dysfunction.

Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., … Kaufer, D. Science Translational Medicine. [In Press]

Paroxysmal slow cortical activity in Alzheimer’s disease and epilepsy is associated with blood-brain barrier dysfunction

Milikovsky, D. Z., Ofer, J., Senatorov, V. V., Friedman, A. R., Sheintuch, L., Elazari, N., ... Kaufer, D., Friedman, A. Science Translational Medicine. [In Press]

2017/

TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults.

Kim, S. Y., Senatorov, V. V., Morrissey, C. S., Lippmann, K., Vazquez, O., Milikovsky, D. Z., … Kaufer, D. Scientific Reports. https://doi.org/10.1038/s41598-017-07394-3

First in vivo traumatic brain injury imaging via magnetic particle imaging.

Orendorff, R., Peck, A. J., Zheng, B., Shirazi, S. N., Matthew Ferguson, R., … Kaufer, D., Conolly, S. Physics in Medicine and Biology. https://doi.org/10.1088/1361-6560/aa52ad

2016/

A potential role for glia-derived extracellular matrix remodeling in postinjury epilepsy.

Kim, S. Y., Porter, B. E., Friedman, A., & Kaufer, D. Journal of Neuroscience Research. https://doi.org/10.1002/jnr.23758

2015/

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction.

Weissberg, I., Wood, L., Kamintsky, L., Vazquez, O., Milikovsky, D. Z., Alexander, A., … Kaufer, D. Neurobiology of Disease. https://doi.org/10.1016/j.nbd.2015.02.029

2014/

Losartan prevents acquired epilepsy via TGF-β signaling suppression.

Bar-Klein, G., Cacheaux, L. P., Kamintsky, L., Prager, O., Weissberg, I., … Kaufer, D., Friedman, A. Annals of Neurology. https://doi.org/10.1002/ana.24147

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