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Select Blood-Brain Barrier Publications

Blood–brain barrier dysfunction promotes astrocyte senescence through albumin-induced TGFβ signaling activation. (2023). Aging Cell. Preininger, M. K., Zaytseva, D., Lin, J. M., Kaufer, D.


Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players. (2020) BRAIN. 

Veksler, R., Vazana, U., Serlin,Y., Prager O., Ofer, J., Shemen, N., Fisher, A. M., Minaeva, O., Hua, N., Saar-Ashkenazy, R., Benou, I., Riklin-Raviv, T., Parker, E., Mumby, G., Kamintsky, L., Beyea, S., Bowen, C. V., Shelef, I., O’Keeffe,E., Campbell, M., Kaufer, D, Goldstein, L. E., Friedman, A.

Blood‐brain barrier dysfunction in canine epileptic seizures detected by dynamic contrast‐enhanced magnetic resonance imaging.  (2019) Epilepsia. Hanael, E., Veksler, R., Friedman, A., Bar-Klein, G., Senatorov Jr, V. V., Kaufer, D., Konstantin, L., Elkin, M., Chai, O., Peery, D., Shamir, M. H.

Blood-brain barrier dysfunction in aging induces hyper-activation of TGF-beta signaling and chronic yet reversible neural dysfunction. (2019) 
Science Translational Medicine. Senatorov, V. V., Friedman, A. R., Milikovsky, D. Z., Ofer, J., Saar-Ashkenazy, R., Charbash, A., … Kaufer, D.

Paroxysmal slow cortical activity in Alzheimer’s disease and epilepsy is associated with blood-brain barrier dysfunction. (2019) Science Translational Medicine. Milikovsky, D. Z., Ofer, J., Senatorov, V. V., Friedman, A. R., Sheintuch, L., Elazari, N., ... Kaufer, D., Friedman, A.

Concussion, Microvascular Injury, and Phosphorylated Tauopathy in Young Athletes after Impact Head Injury and an Impact Concussion Mouse Model. (2018) BRAIN. Tagge CA, Fisher AM, Minaeva OV et al.....Goldstein L.

TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults. (2017) Scientific Reports. Kim, S. Y., Senatorov, V. V., Morrissey, C. S., Lippmann, K., Vazquez, O., Milikovsky, D. Z., … Kaufer, D.

A potential role for glia-derived extracellular matrix remodeling in postinjury epilepsy. (2016) Journal of Neuroscience Research. Kim, S. Y., Porter, B. E., Friedman, A., & Kaufer, D.

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction. (2015) Neurobiology of Disease. Weissberg, I., Wood, L., Kamintsky, L., Vazquez, O., Milikovsky, D. Z., Alexander, A., … Kaufer, D.

Losartan prevents acquired epilepsy via TGF-β signaling suppression. (2014) Annals of Neurology. Bar-Klein, G., Cacheaux, L. P., Kamintsky, L., Prager, O., Weissberg, I., … Kaufer, D., Friedman, A.



Regional gray matter oligodendrocyte-and myelin-related measures are associated with differential susceptibility to stress-induced behavior in rats and humans. (2021) Translational Psychiatry. Long, K. L. P., Chao, L. L., Kazama, Y., An, A., ... Kaufer, D.

Juvenile exposure to acute traumatic stress leads to long-lasting alterations in grey matter myelination in adult female but not male rats. (2021) Neurobiology of Stress. Breton J.M., Barraza M, Hu K.Y., Frias S.J., Long KLP, Kaufer D.

Stress, social behavior, and resilience: insights from rodents. (2015) 
Neurobiol Stress. Beery AK, Kaufer D.

Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. (2014) Mol Psychiatry. Chetty S, Friedman AR, Taravosh-Lahn K, Kirby ED, Mirescu C, Guo F, Krupik D, Nicholas A, Geraghty A, Krishnamurthy A, Tsai MK, Covarrubias D, Wong A, Francis D, Sapolsky RM, Palmer TD, Pleasure D, Kaufer D.

Acute stress enhances adult rat hippocampal neurogenesis and activation of n
ewborn neurons via secreted astrocytic FGF2. (2013) Elife. Kirby ED, Muroy SE, Sun WG, Covarrubias D, Leong MJ, Barchas LA, Kaufer D.

                                                   Other Select Publications


Underfeeding Alters Brain Tissue Synthesis Rate in a Rat Brain Injury Model. (2023). International Journal of Molecular Sciences. Curl, C. C., Leija, R. G., Arevalo, J. A., Osmond, A., Duong, J. J., Kaufer, D., Horning, M. A., Brooks, G. A.


Evolutionary modeling suggests that addictions may be driven by competition-induced microbiome dysbiosis. (2023). Communications Biology. Lewin-Epstein, O., Jaques, Y., Feldman, M. W., Kaufer, D., Hadany L.


Neural activation associated with outgroup helping in adolescent rats. (2022). Iscience. Breton J. M., Eisner, J., Gandhi, V. S., Musick, N., Zhang, A., ...  Kaufer, D., Ben-Ami Bartal, I.

Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction. (2022). BRAIN. Parker, E., Aboghazleh, R., Mumby, G., Veksler, R., Ofer, J., Newton, J., Smith, R., Kamintsky, L. ... Kaufer, D., Friedman, A.


Neural correlates of ingroup bias for prosociality in rats. (2021). eLife. Ben-Ami Bartal, I., Breton, J. M., Sheng, H., Long, K. P. L., Chen, S., Halliday, A., Kenney, J. W., Wheeler, A. L., Frankland, P., Shilyansky, C., Deisseroth, K., Keltner, D., Kaufer, D. DOI:


Critical period regulation across multiple timescales. (2020). National Academy of Sciences. Reh, R. K., Dias, B. G., Nelson, C. A. III, Kaufer, D., Werker, J. F., Kolb, B., Levine, J. D., Hensch, T. K. 



Select Stress Publications

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